Insanity

(Player's Handbook v.3.5, p. 244)

Enchantment (Compulsion) [Mind-Affecting]
Level: Jester 6, Sorcerer 7, Wizard 7, Sha'ir 7, Limbo 6, Madness 7, Charm 7, Moon 7,
Components: V, S,
Casting Time: 1 standard action
Range: Medium (100 ft. + 10 ft./level)
Target: One living creature
Duration: Instantaneous
Saving Throw: Will negates
Spell Resistance: Yes

The affected creature suffers from a continuous confusion effect, as the spell.

Remove curse does not remove insanity. Greater restoration, heal, limited wish, miracle, or wish can restore the creature.